by sargent.centre@imperial.ac.uk | Jan 27, 2026
Abstract: Knowledge of solubility curves for active pharmaceutical ingredients (APIs) in organic solvents and solvent mixtures is essential for pharmaceutical process engineering, impacting synthesis in flow reactors, scale-up, crystallization, and purification....
by sargent.centre@imperial.ac.uk | Dec 17, 2025
The current extract-make-use-dispose paradigm throughout product supply chains has enormous environmental and socioeconomic impacts, including climate change, biodiversity loss, depletion of natural resources, and pollution. Policymakers and industry practitioners...
by sargent.centre@imperial.ac.uk | Dec 17, 2025
Pharmaceutical research is constantly looking into unmet medical needs and addressing them with new, more active and specific molecules that bring greater value to patients. To do this; the molecular structures of active pharmaceutical ingredients (API) are becoming...
by sargent.centre@imperial.ac.uk | Dec 17, 2025
The pharmaceutical and biopharmaceutical industry stands as a unique sector, driven by great innovation yet bound by deep-rooted conservatism. The discovery and manufacture of novel drugs and therapies unfold within a highly regulated environment that both safeguards...
by sargent.centre@imperial.ac.uk | Dec 11, 2025
Nonlinear optimization problems present significant computational challenges due to their inherent nonconvexity. In this talk, we explore how machine learning can be integrated into key algorithmic components of nonlinear optimization solvers to enhance their...
