by sargent.centre@imperial.ac.uk | Jul 23, 2025
Bioprocesses play a critical role in producing enzymes, hormones, antibodies, and other high-value proteins for sectors ranging from pharmaceuticals to food and consumer goods. One major challenge in this field is predicting whether these engineered proteins will be...
by sargent.centre@imperial.ac.uk | Jul 23, 2025
Experimental research in chemical engineering and biotechnology often involves vast design spaces, expensive experiments, and competing objectives. Whether it is tuning process conditions for a reactor or screening hundreds of enzyme variants for improved activity,...
by sargent.centre@imperial.ac.uk | May 9, 2025
Integration of continuous flow processing, online process analytical technology, real-time process control, predictive modelling and artificial intelligence (AI) has the potential to deliver self-optimising platforms for screening and manufacturing nanocrystalline...
by sargent.centre@imperial.ac.uk | May 9, 2025
We are pioneering the use of integrated, computer-based systems comprised of simulation, analytics and advanced process optimisation tools to develop autonomous reaction systems. These systems are employed to identify kinetic models online for model-based reaction...
by sargent.centre@imperial.ac.uk | May 9, 2025
Within the context of an EPSRC Prosperity Partnership on “Transforming synthetic drug manufacturing: novel processes, methods and tools”, our team of researchers are developing a knowledge-driven systems engineering framework for analytical and preparative HPLC...
